Externalized Glycolytic Enzymes Are Novel, Conserved, and Early Biomarkers of Apoptosis*
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چکیده
منابع مشابه
Externalized glycolytic enzymes are novel, conserved, and early biomarkers of apoptosis.
The intriguing cell biology of apoptotic cell death results in the externalization of numerous autoantigens on the apoptotic cell surface, including protein determinants for specific recognition, linked to immune responses. Apoptotic cells are recognized by phagocytes and trigger an active immunosuppressive response ("innate apoptotic immunity" (IAI)) even in the absence of engulfment. IAI is r...
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A cDNA library was made with mRNA from Candida albicans grown under conditions favoring the hyphal form. The library was screened for sequences that encode immunogenic proteins by using pooled sera from five patients with oral candidiasis and five uninfected patients. Most of these patients were human immunodeficiency virus positive. From 40,000 cDNA clones screened, 83 positive clones were ide...
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A number of workers have studied the carbohydrate metabolism of sea-urchin eggs and have expressed different opinions about the pathway of carbohydrate breakdown in these eggs. The choice has rested between the breakdown of hexose via the 'hexose monophosphate shunt' and a glycolytic mechanism like that in yeast and muscle, followed by oxidation via the tricarboxylic acid cycle. Rothschild (195...
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Although the dermatophytes are common fungal pathogens, very little is known concerning their metabolic systems. Biochemical studies with this group have been limited primarily to the nutritional requirements (Robbins et al., 1942; Schopfer and Blumer, 1943; Robbins and Ma, 1945; Georg, 1950; Benham, 1953; Silva, 1953; and Silva and Benham, 1954) and the demonstration of various extracellular e...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2012
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.314971